ARRANGED CHRONOLOGICALLY
1. THE GENERATION OF THE FIRST MONOCLONAL T CELLS
Long term culture of tumour-specific cytotoxic T cells
Monoclonal Cytolytic T-Cell Lines
2. THE CREATION OF THE IL2 BIOASSY
T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity
3. THE DEMONSTRATION THAT IL1 and IL2 ARE DISTINCT CYTOKINES
4. THE DISCOVERY OF THE IL2 MOLECULE
Heterogeneity of Human T-Cell Growth Factor(s) Due to Variable Glycosylation
Production and Characterization of Monoclonal Antibodies to Human Interleukin 2: Strategy and Tactics
5. THE DISCOVERY OF IL2 RECEPTORS
T-Cell Growth Factor Receptors: Quantitation, specificity and biological relevance
6. THE IDENTIFICATION OF THE FIRST IL2 RECEPTOR MONOCLONAL ANTIBODY & THE DISCOVERY OF THE FIRST IL2 RECEPTOR CHAIN
A Monoclonal Antibody that Appears to Recognize the Receptor for Human T-Cell Growth Factor; Partial Characterization of the Receptor
7. THE DISCOVERY OF THE MECHANISM OF IMMUNOSUPRESSION BY GLUCOCORTICOIDS
Glucocorticoid Receptors and Glucocorticoid Sensitivity of Mitogen Stimulated and Unstimulated Human Lymphocytes
Glucocorticoid-induced Inhibition of T Cell Growth Factor Production
8. THE DISCOVERY THAT IL2 PROMOTES T CELL GROWTH
Transient Expression of Interleukin 2 Receptors
The Interleukin-2 T-Cell System: A New Cell Growth Model
9. THE FIRST DESCRIPTION OF IL2-INDUCED GENE EXPRESSION
Interleukin-2 Induction of T-Cell G1 Progression and C-myb Expression
10. THE DEVELOPMENT OF NOVEL METHODS TO ISOLATE IL2-INDUCED GENES
Isolation of Interleukin-2 Induced Immediate-Early Genes
11. THE MOLECULAR DEFINITION OF MEMORY T CELLS
Differentiation of T Cell Lymphokine Gene Expression: The In Vitro Acquisition of T Cell Memory
12. THE DEVELOPMENT OF A NEW NON-TOXIC DOSING REGIMEN FOR IL2 THERAPY
Rational Interleukin 2 Therapy for HIV Positive Individuals: Daily Low Doses Enhance Immune Function without Toxicity
Restoration of Immunity with Interleukin-2 Therapy
Cessation of HAART Plus Daily Low-Dose Interleukin 2 to Promote Immunity to HIV
Presentation on Interleukin-2 Immune Restoration: Generating Immunity to HIV, delivered at the 1999 Community Forum on Immune Based Therapies in Boston
Interleukin 2Immunostimulation
In Vivo assessment of Antiviral Reactivity in Chronic HIV Infection
Low Dose Daily Interleukin 2 Immunotherapy: Accelerating Immune Restoration & Expanding HIV-Specific T cell Immunity Without Toxicity
Low Dose Daily Subcutaneous Interleukin 2 in Combination with Highly Active Anti-Retroviral Therapy in HIV+ Patients: A Randomized Controlled Trial
To Cure Chronic HIV Infection, A New Therapeutic Strategy is Needed
Interleukin 2 (IL2)
· Encyclopedia of Hormones, August 22, 2002 [PDF FILE]
The Continuing HIV Vaccine Saga: Naked
Emperors Alongside Fairly Godmothers
13. ADDITIONAL INFORMATION AS TO THE MECHANISMS
RESPONSIBLE FOR SIGNALING CELL GROWTH
Deciding
to Divide: How do Cells Decide?
·
Journal of
Biological Physics, 2005; 31: 261-272, 2005 [PDF FILE]
14.
THE QUANTAL
THEORY OF IMMUNITY
The Quantal Theory of How the Immune
System Discriminates between "Self and nonself"
The Quantal Theory of Immunity